Certified Gastroenterology Registered Nurse Practice Exam 2025 - Free CGRN Practice Questions and Study Guide

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What is a potential outcome of not addressing toxic megacolon?

Improved gut motility

Colonic perforation

Toxic megacolon is a serious condition characterized by extreme dilation of the colon, which can lead to significant complications if not addressed promptly. One of the most severe outcomes associated with untreated toxic megacolon is colonic perforation.

In cases of toxic megacolon, the pressure within an overly distended colon can increase to a critical point, compromising the integrity of the colonic wall. If the wall becomes too thin or weakened, it can lead to perforation, resulting in the leakage of intestinal contents into the abdominal cavity. This situation can provoke severe peritonitis, a life-threatening infection of the abdominal lining, and requires immediate medical intervention, often necessitating surgical procedures.

Understanding the potential for colonic perforation underscores the importance of recognizing and managing toxic megacolon promptly to prevent such devastating outcomes.

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Reduced risk of colon cancer

Decrease in abdominal bloating

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